Increased neurofilament light chain blood levels in neurodegenerative neurological diseases.

Increased neurofilament light chain blood levels in neurodegenerative neurological diseases.

Neuronal damage is the morphological substrate of persisting neurological disability. Neurofilaments (Nf) are cytoskeletal proteins of neurons and their release into cerebrospinal fluid has shown encouraging results as a biomarker for neurodegeneration. This study aimed to validate the quantificatio...

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Bibliographic Details
Main Authors: Johanna Gaiottino, Niklas Norgren, Ruth Dobson, Joanne Topping, Ahuva Nissim, Andrea Malaspina, Jonathan P Bestwick, Andreas U Monsch, Axel Regeniter, Raija L Lindberg, Ludwig Kappos, David Leppert, Axel Petzold, Gavin Giovannoni, Jens Kuhle
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3779219?pdf=render

Internet

http://europepmc.org/articles/PMC3779219?pdf=render

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