Structural basis for the ABO blood-group dependence of Plasmodium falciparum rosetting.

Structural basis for the ABO blood-group dependence of Plasmodium falciparum rosetting.

The ABO blood group influences susceptibility to severe Plasmodium falciparum malaria. Recent evidence indicates that the protective effect of group O operates by virtue of reduced rosetting of infected red blood cells (iRBCs) with uninfected RBCs. Rosetting is mediated by a subgroup of PfEMP1 adhes...

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Main Authors: Inès Vigan-Womas, Micheline Guillotte, Alexandre Juillerat, Audrey Hessel, Bertrand Raynal, Patrick England, Jacques H Cohen, Olivier Bertrand, Thierry Peyrard, Graham A Bentley, Anita Lewit-Bentley, Odile Mercereau-Puijalon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22807674/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22807674/?tool=EBI

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