Mitochondrial Nicotinic Acetylcholine Receptors Support Liver Cells Viability After Partial Hepatectomy

Mitochondrial Nicotinic Acetylcholine Receptors Support Liver Cells Viability After Partial Hepatectomy

Nicotinic acetylcholine receptors (nAChRs) expressed on the cell plasma membrane are ligand-gated ion channels mediating fast synaptic transmission, regulating neurotransmitter and cytokine release and supporting the viability of many cell types. The nAChRs expressed in mitochondria regulate the rel...

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Bibliographic Details
Main Authors: Kateryna Uspenska, Olena Lykhmus, Maria Obolenskaya, Stephanie Pons, Uwe Maskos, Serhiy Komisarenko, Maryna Skok
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Pharmacology
Subjects:
nicotinic acetylcholine receptor
mitochondria
knockout mice
partial hepatectomy
cytochrome c
mitochondrial kinases
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.00626/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2018.00626/full

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