Beneficial Effect of Exercise on Cognitive Function during Peripheral Arterial Disease: Potential Involvement of Myokines and Microglial Anti-Inflammatory Phenotype Enhancement

Beneficial Effect of Exercise on Cognitive Function during Peripheral Arterial Disease: Potential Involvement of Myokines and Microglial Anti-Inflammatory Phenotype Enhancement

Peripheral arterial disease (PAD), leading to intermittent claudication, critical ischemia with rest pain, and/or tissue damage, is a public health issue associated with significant morbidity and mortality. Little is known about the link between PAD, cognitive function, and whether exercise might re...

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Bibliographic Details
Main Authors: Marina Leardini-Tristao, Anne-Laure Charles, Anne Lejay, Mégane Pizzimenti, Alain Meyer, Vanessa Estato, Eduardo Tibiriçá, Emmanuel Andres, Bernard Geny
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Journal of Clinical Medicine
Subjects:
peripheral arterial disease
ankle-brachial index
cognitive dysfunction
brain
exercise
myokines
microglia
BDNF
cathepsin-B
irisin
Online Access:https://www.mdpi.com/2077-0383/8/5/653

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https://www.mdpi.com/2077-0383/8/5/653

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