Thymoquinone synergistically potentiates temozolomide cytotoxicity through the inhibition of autophagy in U87MG cell line

Objective(s): Glioblastoma multiforme (GBM) is one of the most lethal forms of human cancer and temozolomide (TMZ) is currently part of the standard treatment for this disease. Combination therapy using natural substances can enhance the anti-cancer activity of TMZ. The purpose of this study was to...

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Bibliographic Details
Main Authors: Mona Pazhouhi, Reyhaneh Sariri, Arezou Rabzia, Mozafar Khazaei
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2016-08-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Online Access:http://ijbms.mums.ac.ir/article_7472_5e1a4ecb241c797f441ac4f113e01657.pdf