Understanding aneuploidy in cancer through the lens of system inheritance, fuzzy inheritance and emergence of new genome systems

Abstract Background In the past 15 years, impressive progress has been made to understand the molecular mechanism behind aneuploidy, largely due to the effort of using various -omics approaches to study model systems (e.g. yeast and mouse models) and patient samples, as well as the new realization t...

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Bibliographic Details
Main Authors: Christine J. Ye, Sarah Regan, Guo Liu, Sarah Alemara, Henry H. Heng
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Molecular Cytogenetics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13039-018-0376-2