Case Report: Primary Immunodeficiencies, Massive EBV+ T-Cell Lympoproliferation Leading to the Diagnosis of ICF2 Syndrome

Case Report: Primary Immunodeficiencies, Massive EBV+ T-Cell Lympoproliferation Leading to the Diagnosis of ICF2 Syndrome

In immunocompromised patients, EBV may elicit B-cell transformation and proliferation. A 5-year-old microcephalic boy was admitted with fever and non-malignant polymorphic T-cell lymphoproliferative disease associated with EBV. A presumptive diagnosis of primary immunodeficiency with inability to co...

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Bibliographic Details
Main Authors: Gonçalo Luzes Padeira, Catarina Araújo, Ana Isabel Cordeiro, João Freixo, Catarina Gregório Martins, João Farela Neves
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Immunology
Subjects:
case report
ICF-2
Primary immune deficiencies
EBV
lymphoproliferation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.654167/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.654167/full

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