Mitochondrial Enzymes of the Urea Cycle Cluster at the Inner Mitochondrial Membrane

Mitochondrial Enzymes of the Urea Cycle Cluster at the Inner Mitochondrial Membrane

Mitochondrial enzymes involved in energy transformation are organized into multiprotein complexes that channel the reaction intermediates for efficient ATP production. Three of the mammalian urea cycle enzymes: N-acetylglutamate synthase (NAGS), carbamylphosphate synthetase 1 (CPS1), and ornithine t...

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Bibliographic Details
Main Authors: Nantaporn Haskins, Shivaprasad Bhuvanendran, Claudio Anselmi, Anna Gams, Tomas Kanholm, Kristen M. Kocher, Jonathan LoTempio, Kylie I. Krohmaly, Danielle Sohai, Nathaniel Stearrett, Erin Bonner, Mendel Tuchman, Hiroki Morizono, Jyoti K. Jaiswal, Ljubica Caldovic
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Physiology
Subjects:
urea cycle
N-acetylglutamate synthase
carbamylphosphate synthetase 1
ornithine transcarbamylase
enzyme cluster
mitochondria
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2020.542950/full

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https://www.frontiersin.org/articles/10.3389/fphys.2020.542950/full

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