QSAR ANALYSIS OF COMPLEXATION OF ETHERS OF 7-BROM-3-HYDROXY-5-(2'-CHLORO) PHENYL-1,2-DIHYDRO-3H-1,4-BENZODIAZEPIN-2-ONES WITH CENTRAL BENZODIAZEPINE RECEPTORS CNS

QSAR ANALYSIS OF COMPLEXATION OF ETHERS OF 7-BROM-3-HYDROXY-5-(2'-CHLORO) PHENYL-1,2-DIHYDRO-3H-1,4-BENZODIAZEPIN-2-ONES WITH CENTRAL BENZODIAZEPINE RECEPTORS CNS

QSAR analysis of the structural infl uence of 3-substituted 1,2-dihydro-3Н-1,4-benzodiazepine derivatives on the thermodynamic characteristics (ΔН0, ΔS0 and ΔG0) of their complexation with compounds was the main problem of QSAR analysis in this study. For small sets a new approach was developed for...

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Bibliographic Details
Main Authors: E. A. Lukianova, L. N. Ognichenko, T. A. Yurpalova, N. A. Burenkova, S. P. Smulsky, V. I. Pavlovsky, S. A. Andronati, V. E. Kuz`min
Format: Article
Language:English
Published: Odessa I. I. Mechnikov National University 2018-02-01
Series:Vìsnik Odesʹkogo Nacìonalʹnogo Unìversitetu: Hìmìâ
Subjects:
QSAR аналіз
бенздіазепінові рецептори
термодинаміка комплексоутворення
симплексне представлення молекулярної структури
Online Access:http://heraldchem.onu.edu.ua/article/view/124547

Internet

http://heraldchem.onu.edu.ua/article/view/124547

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