Histone demethylase KDM4D promotes gastrointestinal stromal tumor progression through HIF1β/VEGFA signalling

Histone demethylase KDM4D promotes gastrointestinal stromal tumor progression through HIF1β/VEGFA signalling

Abstract Background Gastrointestinal stromal tumour (GIST) is the most common soft tissue sarcoma. The identification of the molecular mechanisms regulating GIST progression is vital for its treatment and prevention. Increasing reports have demonstrated that epigenetic alterations play critical role...

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Bibliographic Details
Main Authors: Fuqing Hu, Haijie Li, Lu Liu, Feng Xu, Senyan Lai, Xuelai Luo, Junbo Hu, Xi Yang
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Molecular Cancer
Subjects:
GIST - KDM4D
Proliferation
Migration
Angiogenesis
Online Access:http://link.springer.com/article/10.1186/s12943-018-0861-6

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http://link.springer.com/article/10.1186/s12943-018-0861-6

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