Transient receptor potential ankyrin 1 receptor activation in vitro and in vivo by pro-tussive agents: GRC 17536 as a promising anti-tussive therapeutic.

Cough is a protective reflex action that helps clear the respiratory tract which is continuously exposed to airborne environmental irritants. However, chronic cough presents itself as a disease in its own right and despite its global occurrence; the molecular mechanisms responsible for cough are not...

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Main Authors: Indranil Mukhopadhyay, Abhay Kulkarni, Sarika Aranake, Pallavi Karnik, Mahesh Shetty, Sandeep Thorat, Indraneel Ghosh, Dinesh Wale, Vikram Bhosale, Neelima Khairatkar-Joshi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4018403?pdf=render