TB and SIV Coinfection; a Model for Evaluating Vaccine Strategies against TB Reactivation in Asian Origin Cynomolgus Macaques: A Pilot Study Using BCG Vaccination

TB and SIV Coinfection; a Model for Evaluating Vaccine Strategies against TB Reactivation in Asian Origin Cynomolgus Macaques: A Pilot Study Using BCG Vaccination

This pilot study aimed to determine the utility of a cynomolgus macaque model of coinfection with simian immunodeficiency virus (SIV) for the assessment of vaccines designed to prevent reactivation of TB. Following infection caused by aerosol exposure to an ultralow dose of <i>Mycobacterium tu...

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Bibliographic Details
Main Authors: Andrew D. White, Laura Sibley, Jennie Gullick, Charlotte Sarfas, Simon Clark, Zahra Fagrouch, Ernst Verschoor, Francisco J. Salguero, Mike Dennis, Sally Sharpe
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Vaccines
Subjects:
tuberculosis
SIV
macaques
coinfection
reactivation
Online Access:https://www.mdpi.com/2076-393X/9/9/945

Internet

https://www.mdpi.com/2076-393X/9/9/945

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