Comparison of 68Ga-DOTA-Siglec-9 and 18F-Fluorodeoxyribose-Siglec-9: Inflammation Imaging and Radiation Dosimetry

Comparison of 68Ga-DOTA-Siglec-9 and 18F-Fluorodeoxyribose-Siglec-9: Inflammation Imaging and Radiation Dosimetry

Sialic acid-binding immunoglobulin-like lectin 9 (Siglec-9) is a ligand of inflammation-inducible vascular adhesion protein-1 (VAP-1). We compared 68Ga-DOTA- and 18F-fluorodeoxyribose- (FDR-) labeled Siglec-9 motif peptides for PET imaging of inflammation. Methods. Firstly, we examined 68Ga-DOTA-Sig...

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Bibliographic Details
Main Authors: Helena Virtanen, Johanna M. U. Silvola, Anu Autio, Xiang-Guo Li, Heidi Liljenbäck, Sanna Hellberg, Riikka Siitonen, Mia Ståhle, Meeri Käkelä, Anu J. Airaksinen, Kerttuli Helariutta, Tuula Tolvanen, Tibor Z. Veres, Antti Saraste, Juhani Knuuti, Sirpa Jalkanen, Anne Roivainen
Format: Article
Language:English
Published: Hindawi-Wiley 2017-01-01
Series:Contrast Media & Molecular Imaging
Online Access:http://dx.doi.org/10.1155/2017/7645070

Internet

http://dx.doi.org/10.1155/2017/7645070

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