GSK3β N-terminus binding to p53 promotes its acetylation

<p>Abstract</p> <p>The prevalence in human cancers of mutations in p53 exemplifies its crucial role as a tumor suppressor transcription factor. Previous studies have shown that the constitutively active serine/threonine kinase glycogen synthase kinase-3β (GSK3β) associates with the...

Full description

Bibliographic Details
Main Authors: Eom Tae-Yeon, Jope Richard S
Format: Article
Language:English
Published: BMC 2009-03-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/8/1/14