Serum level of hemokinin-1 is significantly lower in patients with chronic spontaneous urticaria than in healthy subjects

Serum level of hemokinin-1 is significantly lower in patients with chronic spontaneous urticaria than in healthy subjects

Background: We previously reported upregulation of expression of Mas–related G protein–coupled receptor X2 (MRGPRX2) on mast cells (MCs) in the skin of patients with severe chronic spontaneous urticaria (CSU). Serum levels of substance P (SP) were reportedly significantly elevated, in correlation wi...

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Bibliographic Details
Main Authors: Nobuyuki Nishimori, Shota Toyoshima, Tomomi Sasaki-Sakamoto, Koremasa Hayama, Tadashi Terui, Yoshimichi Okayama
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:Allergology International
Subjects:
Autoantibody
Basophil/mast cell
FcεRIα
Immunoglobulin E
Urticaria
Online Access:http://www.sciencedirect.com/science/article/pii/S1323893021000514

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http://www.sciencedirect.com/science/article/pii/S1323893021000514

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