APOBEC4 Enhances the Replication of HIV-1.

APOBEC4 Enhances the Replication of HIV-1.

APOBEC4 (A4) is a member of the AID/APOBEC family of cytidine deaminases. In this study we found a high mRNA expression of A4 in human testis. In contrast, there were only low levels of A4 mRNA detectable in 293T, HeLa, Jurkat or A3.01 cells. Ectopic expression of A4 in HeLa cells resulted in mostly...

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Bibliographic Details
Main Authors: Daniela Marino, Mario Perković, Anika Hain, Ananda A Jaguva Vasudevan, Henning Hofmann, Kay-Martin Hanschmann, Michael D Mühlebach, Gerald G Schumann, Renate König, Klaus Cichutek, Dieter Häussinger, Carsten Münk
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4889046?pdf=render

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http://europepmc.org/articles/PMC4889046?pdf=render

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