In Situ Absorption in Rat Intestinal Tract of Solid Dispersion of Annonaceous Acetogenins

Isolated from Annona squamosa L, Annonaceous acetogenins (ACGs) exhibit a broad range of biological properties yet absorbed badly due to the low solubility. Solid dispersion in polyethylene glycol 4000 (PEG 4000) has been developed to increase the solubility and oral absorption of ACGs. The formulat...

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Bibliographic Details
Main Authors: Yun-Jie Dang, Han-Zhou Feng, Limei Zhang, Chun-Hui Hu, Chun-Yan Zhu
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Gastroenterology Research and Practice
Online Access:http://dx.doi.org/10.1155/2012/879676