Manganese Superoxide Dismutase Dysfunction and the Pathogenesis of Kidney Disease

Manganese Superoxide Dismutase Dysfunction and the Pathogenesis of Kidney Disease

The mitochondria are a major source of reactive oxygen species (ROS). Superoxide anion (O2•–) is produced by the process of oxidative phosphorylation associated with glucose, amino acid, and fatty acid metabolism, resulting in the production of adenosine triphosphate (ATP) in the mitochondria. Exces...

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Bibliographic Details
Main Authors: Munehiro Kitada, Jing Xu, Yoshio Ogura, Itaru Monno, Daisuke Koya
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Physiology
Subjects:
manganese superoxide dismutase
acute kidney injury
chronic kidney disease
mitochondria
peroxynitrite
posttranslational modification
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2020.00755/full

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https://www.frontiersin.org/article/10.3389/fphys.2020.00755/full

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