Synthesis and targeting of gold-coated 177Lu-containing lanthanide phosphate nanoparticles—A potential theranostic agent for pulmonary metastatic disease

Synthesis and targeting of gold-coated 177Lu-containing lanthanide phosphate nanoparticles—A potential theranostic agent for pulmonary metastatic disease

Targeted radiotherapies maximize cytotoxicity to cancer cells. In this work, we describe the synthesis, characterization, and biodistribution of antibody conjugated gold-coated lanthanide phosphate nanoparticles containing 177Lu. [177Lu]Lu0.5Gd0.5(PO4)@Au@PEG800@Ab nanoparticles combine the radiatio...

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Bibliographic Details
Main Authors: Nicholas Sobol, Logan Sutherlin, Edyta Cedrowska, Joshua Schorp, Cristina Rodríguez-Rodríguez, Vesna Sossi, Jimmy Lattimer, Douglas C Miller, Paul Pevsner, J. David Robertson
Format: Article
Language:English
Published: AIP Publishing LLC 2018-03-01
Series:APL Bioengineering
Online Access:http://dx.doi.org/10.1063/1.5018165

Internet

http://dx.doi.org/10.1063/1.5018165

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