MHC and KIR polymorphisms in rhesus macaque SIV infection

Natural killer (NK) lymphocytes are essentially involved as the first line of defense against agents such as viruses and malignant cells. The activity of these cells is regulated via interaction of specific and diverse killer cell immunoglobulin-like receptors (KIR) with the highly polymorphic cogna...

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Bibliographic Details
Main Authors: Lutz eWalter, Aftab A Ansari
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-10-01
Series:Frontiers in Immunology
Subjects:
KIR
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00540/full