Bacterial toxicity of potassium tellurite: unveiling an ancient enigma.

Biochemical, genetic, enzymatic and molecular approaches were used to demonstrate, for the first time, that tellurite (TeO(3) (2-)) toxicity in E. coli involves superoxide formation. This radical is derived, at least in part, from enzymatic TeO(3) (2-) reduction. This conclusion is supported by the...

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Bibliographic Details
Main Authors: José M Pérez, Iván L Calderón, Felipe A Arenas, Derie E Fuentes, Gonzalo A Pradenas, Eugenia L Fuentes, Juan M Sandoval, Miguel E Castro, Alex O Elías, Claudio C Vásquez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-02-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC1784070?pdf=render