The Drosophila TGF-beta/Activin-like ligands Dawdle and Myoglianin appear to modulate adult lifespan through regulation of 26S proteasome function in adult muscle

The Drosophila TGF-beta/Activin-like ligands Dawdle and Myoglianin appear to modulate adult lifespan through regulation of 26S proteasome function in adult muscle

The Drosophila Activin signaling pathway employs at least three separate ligands – Activin-β (Actβ), Dawdle (Daw), and Myoglianin (Myo) – to regulate several general aspects of fruit fly larval development, including cell proliferation, neuronal remodeling, and metabolism. Here we provide experiment...

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Bibliographic Details
Main Authors: Shaughna Langerak, Myung-Jun Kim, Hannah Lamberg, Michael Godinez, Mackenzie Main, Lindsey Winslow, Michael B. O'Connor, Changqi C. Zhu
Format: Article
Language:English
Published: The Company of Biologists 2018-04-01
Series:Biology Open
Subjects:
Activin signaling
Dawdle gene
Drosophila
Fruit fly
Lifespan
Myoglianin gene
Online Access:http://bio.biologists.org/content/7/4/bio029454

Internet

http://bio.biologists.org/content/7/4/bio029454

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