Role of Hyaluronan in Human Adipogenesis: Evidence from in-Vitro and in-Vivo Studies

Role of Hyaluronan in Human Adipogenesis: Evidence from in-Vitro and in-Vivo Studies

Hyaluronan (HA), an extra-cellular matrix glycosaminoglycan, may play a role in mesenchymal stem cell differentiation to fat but results using murine models and cell lines are conflicting. Our previous data, illustrating decreased HA production during human adipogenesis, suggested an inhibitory role...

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Bibliographic Details
Main Authors: Nicholas Wilson, Robert Steadman, Ilaria Muller, Mohd Draman, D. Aled Rees, Peter Taylor, Colin M. Dayan, Marian Ludgate, Lei Zhang
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:International Journal of Molecular Sciences
Subjects:
mesenchymal stem cell
Adipogenesis
fat accumulation
Extracellular matrix
hyaluronan
BMI
4-methylumbelliferone
PPARγ
Online Access:https://www.mdpi.com/1422-0067/20/11/2675

Internet

https://www.mdpi.com/1422-0067/20/11/2675

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