Independent association of HLA-DPB1*02:01 with rheumatoid arthritis in Japanese populations.

OBJECTIVE:Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized with joint destructions; environmental and genetic factors were thought to be involved in the etiology of RA. The production of anti-citrullinated peptide antibodies (ACPA) is specifically associated with RA. DRB1 is a...

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Main Authors: Hiroshi Furukawa, Shomi Oka, Kota Shimada, Atsushi Hashimoto, Akiko Komiya, Shinichiro Tsunoda, Akiko Suda, Satoshi Ito, Koichiro Saisho, Masao Katayama, Satoshi Shinohara, Takeo Sato, Katsuya Nagatani, Seiji Minota, Toshihiro Matsui, Naoshi Fukui, Shoji Sugii, Hajime Sano, Kiyoshi Migita, Shouhei Nagaoka, Shigeto Tohma
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6157818?pdf=render