Development of highly organized lymphoid structures in Buruli ulcer lesions after treatment with rifampicin and streptomycin.

BACKGROUND: Buruli ulcer caused by Mycobacterium ulcerans is an infection of the subcutaneous tissue leading to chronic necrotising skin ulcers. The pathogenesis is associated with the cytocidal and immunosuppressive activities of a macrolide toxin. Histopathological hallmark of progressing disease...

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Bibliographic Details
Main Authors: Daniela Schütte, Alphonse Um-Boock, Ernestina Mensah-Quainoo, Peter Itin, Peter Schmid, Gerd Pluschke
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC2041817?pdf=render