Selectin Ligands Sialyl-Lewis a and Sialyl-Lewis x in Gastrointestinal Cancers

Selectin Ligands Sialyl-Lewis a and Sialyl-Lewis x in Gastrointestinal Cancers

The tetrasaccharide structures Siaα2,3Galβ1,3(Fucα1,4)GlcNAc and Siaα2,3Galβ1,4(Fucα1,3)GlcNAc constitute the epitopes of the carbohydrate antigens sialyl-Lewis a (sLea) and sialyl-Lewis x (sLex), respectively, and are the minimal requirement for selectin binding to their counter-receptors. Interact...

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Bibliographic Details
Main Authors: Marco Trinchera, Adele Aronica, Fabio Dall’Olio
Format: Article
Language:English
Published: MDPI AG 2017-02-01
Series:Biology
Subjects:
carbohydrate antigens
glycosylation
cancer diagnosis
cancer malignancy
Online Access:http://www.mdpi.com/2079-7737/6/1/16

Internet

http://www.mdpi.com/2079-7737/6/1/16

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