Representation of CYP3A4, CYP3A5 and UGT1A4 Polymorphisms within Croatian Breast Cancer Patients’ Population

Representation of CYP3A4, CYP3A5 and UGT1A4 Polymorphisms within Croatian Breast Cancer Patients’ Population

Single nucleotide polymorphism (SNP) in genes encoding drug-metabolizing enzymes (DME) could have a critical role in individual responses to anastrozole. Frequency of CYP3A4*1B, CYP3A5*3 and UGT1A4*2 SNPs in 126 Croatian breast cancer (BC) patients and possible association with anastrozole-induced u...

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Bibliographic Details
Main Authors: Kristina Bojanic, Lucija Kuna, Ines Bilic Curcic, Jasenka Wagner, Robert Smolic, Kristina Kralik, Tomislav Kizivat, Gordana Ivanac, Aleksandar Vcev, George Y. Wu, Martina Smolic
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:International Journal of Environmental Research and Public Health
Subjects:
single nucleotide polymorphism
drug metabolizing enzyme
breast cancer therapy
anastrozole
side effects
Online Access:https://www.mdpi.com/1660-4601/17/10/3692

Internet

https://www.mdpi.com/1660-4601/17/10/3692

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