Red blood cell phenotype fidelity following glycerol cryopreservation optimized for research purposes.

Intact red blood cells (RBCs) are required for phenotypic analyses. In order to allow separation (time and location) between subject encounter and sample analysis, we developed a research-specific RBC cryopreservation protocol and assessed its impact on data fidelity for key biochemical and physiolo...

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Bibliographic Details
Main Authors: Stephen C Rogers, Laura B Dosier, Timothy J McMahon, Hongmei Zhu, David Timm, Hengtao Zhang, Joseph Herbert, Jacqueline Atallah, Gregory M Palmer, Asa Cook, Melanie Ernst, Jaya Prakash, Mark Terng, Parhom Towfighi, Reid Doctor, Ahmed Said, Matthew S Joens, James A J Fitzpatrick, Gabi Hanna, Xue Lin, Julie A Reisz, Travis Nemkov, Angelo D'Alessandro, Allan Doctor
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0209201