The Spleen Plays No Role in Nephrotoxic Serum Nephritis, but Constitutes a Place of Compensatory Haematopoiesis.

The spleen has been implicated in the pathogenesis of immune-complex glomerulonephritis by initiating and resolving adaptive immune responses. Thus, we aimed to evaluate the role of the spleen in experimental nephrotoxic serum nephritis (NTS).In order to accelerate the disease, animals were subjecte...

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Bibliographic Details
Main Authors: Katharina Artinger, Alexander H Kirsch, Ida Aringer, Corinna Schabhüttl, Alexander R Rosenkranz, Philipp Eller, Elena Rho, Kathrin Eller
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4527588?pdf=render