UDP-Glycosyltransferases and Albendazole Metabolism in the Juvenile Stages of Haemonchus contortus

UDP-Glycosyltransferases and Albendazole Metabolism in the Juvenile Stages of Haemonchus contortus

The nematode Haemonchus contortus, a gastrointestinal parasite of ruminants, can severely burden livestock production. Although anthelmintics are the mainstay in the treatment of haemonchosis, their efficacy diminishes due to drug-resistance development in H. contortus. An increased anthelmintics in...

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Bibliographic Details
Main Authors: Pavlína Kellerová, Martina Navrátilová, Linh Thuy Nguyen, Diana Dimunová, Lucie Raisová Stuchlíková, Karolína Štěrbová, Lenka Skálová, Petra Matoušková
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Physiology
Subjects:
UGT
biotransformation
drug resistance
nematode
anthelmintics
UHPLC-MS
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2020.594116/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2020.594116/full

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