Metabolomic Profiling of Plasma and Erythrocytes in Sickle Mice Points to Altered Nociceptive Pathways

Metabolomic Profiling of Plasma and Erythrocytes in Sickle Mice Points to Altered Nociceptive Pathways

Few data-driven metabolomic approaches have been reported in sickle cell disease (SCD) to date. We performed a metabo-lipidomic study on the plasma and red blood cells of a steady-state mouse model carrying the homozygous human hemoglobin SS, compared with AS and AA genotypes. Among the 188 metaboli...

Full description

Bibliographic Details
Main Authors: Klétigui Casimir Dembélé, Thomas Mintz, Charlotte Veyrat-Durebex, Floris Chabrun, Stéphanie Chupin, Lydie Tessier, Gilles Simard, Daniel Henrion, Delphine Mirebeau-Prunier, Juan Manuel Chao de la Barca, Pierre-Louis Tharaux, Pascal Reynier
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Cells
Subjects:
metabolomics
lipidomics
nociception
sickle cell disease
Online Access:https://www.mdpi.com/2073-4409/9/6/1334

Internet

https://www.mdpi.com/2073-4409/9/6/1334

Similar Items