Gene-Set Local Hierarchical Clustering (GSLHC)--A Gene Set-Based Approach for Characterizing Bioactive Compounds in Terms of Biological Functional Groups.

Gene-Set Local Hierarchical Clustering (GSLHC)--A Gene Set-Based Approach for Characterizing Bioactive Compounds in Terms of Biological Functional Groups.

Gene-set-based analysis (GSA), which uses the relative importance of functional gene-sets, or molecular signatures, as units for analysis of genome-wide gene expression data, has exhibited major advantages with respect to greater accuracy, robustness, and biological relevance, over individual gene a...

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Bibliographic Details
Main Authors: Feng-Hsiang Chung, Zhen-Hua Jin, Tzu-Ting Hsu, Chueh-Lin Hsu, Hsueh-Chuan Liu, Hoong-Chien Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4652590?pdf=render

Internet

http://europepmc.org/articles/PMC4652590?pdf=render

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