Risks at the DNA Replication Fork: Effects upon Carcinogenesis and Tumor Heterogeneity
The ability of all organisms to copy their genetic information via DNA replication is a prerequisite for cell division and a biological imperative of life. In multicellular organisms, however, mutations arising from DNA replication errors in the germline and somatic cells are the basis of genetic di...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2017-01-01
|
Series: | Genes |
Subjects: | |
Online Access: | http://www.mdpi.com/2073-4425/8/1/46 |