Tropomodulin’s Actin-Binding Abilities Are Required to Modulate Dendrite Development

Tropomodulin’s Actin-Binding Abilities Are Required to Modulate Dendrite Development

There are many unanswered questions about the roles of the actin pointed end capping and actin nucleation by tropomodulins (Tmod) in regulating neural morphology. Previous studies indicate that Tmod1 and Tmod2 regulate morphology of the dendritic arbor and spines. Tmod3, which is expressed in the br...

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Bibliographic Details
Main Authors: Kevin T. Gray, Holly Stefen, Thu N. A. Ly, Christopher J. Keller, Mert Colpan, Gary A. Wayman, Edward Pate, Thomas Fath, Alla S. Kostyukova
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Molecular Neuroscience
Subjects:
neurite outgrowth
actin cytoskeleton
hippocampal neuron culture
tropomodulin
actin dynamics
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2018.00357/full

Internet

https://www.frontiersin.org/article/10.3389/fnmol.2018.00357/full

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