Distribution of mesenchymal stem cells and effects on neuronal survival and axon regeneration after optic nerve crush and cell therapy.

Bone marrow-derived cells have been used in different animal models of neurological diseases. We investigated the therapeutic potential of mesenchymal stem cells (MSC) injected into the vitreous body in a model of optic nerve injury. Adult (3-5 months old) Lister Hooded rats underwent unilateral opt...

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Main Authors: Louise Alessandra Mesentier-Louro, Camila Zaverucha-do-Valle, Almir Jordão da Silva-Junior, Gabriel Nascimento-Dos-Santos, Fernanda Gubert, Ana Beatriz Padilha de Figueirêdo, Ana Luiza Torres, Bruno D Paredes, Camila Teixeira, Fernanda Tovar-Moll, Rosalia Mendez-Otero, Marcelo F Santiago
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4210195?pdf=render