Knock-down of NDRG2 sensitizes cervical cancer Hela cells to cisplatin through suppressing Bcl-2 expression

Knock-down of NDRG2 sensitizes cervical cancer Hela cells to cisplatin through suppressing Bcl-2 expression

<p>Abstract</p> <p>Background</p> <p>NDRG2, a member of N-Myc downstream regulated gene family, plays some roles in cellular stress, cell differentiation and tumor suppression. We have found that NDRG2 expression in cervical cancer Hela cells increases significantly upo...

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Bibliographic Details
Main Authors: Liu Junye, Yang Le, Zhang Jian, Zhang Jing, Chen Yongbin, Li Kangchu, Li Yurong, Li Yan, Yao Libo, Guo Guozhen
Format: Article
Language:English
Published: BMC 2012-08-01
Series:BMC Cancer
Subjects:
Bcl-2
Chemosensitivity
Cisplatin
NDRG2
RNA interference
Online Access:http://www.biomedcentral.com/1471-2407/12/370

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http://www.biomedcentral.com/1471-2407/12/370

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