HCoV- and SARS-CoV-2 Cross-Reactive T Cells in CVID Patients

HCoV- and SARS-CoV-2 Cross-Reactive T Cells in CVID Patients

The inability of patients with CVID to mount specific antibody responses to pathogens has raised concerns on the risk and severity of SARS-CoV-2 infection, but there might be a role for protective T cells in these patients. SARS-CoV-2 reactive T cells have been reported for SARS-CoV-2 unexposed heal...

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Bibliographic Details
Main Authors: Sophie Steiner, Franziska Sotzny, Sandra Bauer, Il-Kang Na, Michael Schmueck-Henneresse, Victor M. Corman, Tatjana Schwarz, Christian Drosten, Désirée J. Wendering, Uta Behrends, Hans-Dieter Volk, Carmen Scheibenbogen, Leif G. Hanitsch
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Immunology
Subjects:
common variable immunodeficiency disorder (CVID)
coronavirus disease 2019 (COVID-19)
T cell response
primary immunodeficiency (PID)
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
human endemic coronavirus 229E (HCoV-229E)
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.607918/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2020.607918/full

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