Identification of BRCA1/2 founder mutations in Southern Chinese breast cancer patients using gene sequencing and high resolution DNA melting analysis.

Identification of BRCA1/2 founder mutations in Southern Chinese breast cancer patients using gene sequencing and high resolution DNA melting analysis.

Ethnic variations in breast cancer epidemiology and genetics have necessitated investigation of the spectra of BRCA1 and BRCA2 mutations in different populations. Knowledge of BRCA mutations in Chinese populations is still largely unknown. We conducted a multi-center study to characterize the spectr...

Full description

Bibliographic Details
Main Authors: Ava Kwong, Enders Kai On Ng, Chris Lei Po Wong, Fian Bic Fai Law, Tommy Au, Hong Nei Wong, Allison W Kurian, Dee W West, James M Ford, Edmond Siu Kwan Ma
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3436879?pdf=render

Internet

http://europepmc.org/articles/PMC3436879?pdf=render

Similar Items