The Innate Immune DNA Sensing cGAS-STING Signaling Pathway Mediates Anti-PRRSV Function

The Innate Immune DNA Sensing cGAS-STING Signaling Pathway Mediates Anti-PRRSV Function

Porcine reproductive and respiratory syndrome virus (PRRSV) modulates host innate immunity which plays a key role against PRRSV infection. As a RNA virus, PRRSV is mainly sensed by innate immune RNA receptors, whereas the role of innate immune DNA sensors in the PRRSV infection has not been elucidat...

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Bibliographic Details
Main Authors: Yulin Xu, Youwen Zhang, Shaohua Sun, Jia Luo, Sen Jiang, Jiajia Zhang, Xueliang Liu, Qi Shao, Qi Cao, Wanglong Zheng, Nanhua Chen, François Meurens, Jianzhong Zhu
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Viruses
Subjects:
PRRSV
innate immunity
DNA sensor
cGAS-STING
antiviral activity
Online Access:https://www.mdpi.com/1999-4915/13/9/1829

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https://www.mdpi.com/1999-4915/13/9/1829

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