Prediction of post-radiotherapy locoregional progression in HPV-associated oropharyngeal squamous cell carcinoma using machine-learning analysis of baseline PET/CT radiomics

Prediction of post-radiotherapy locoregional progression in HPV-associated oropharyngeal squamous cell carcinoma using machine-learning analysis of baseline PET/CT radiomics

Locoregional failure remains a therapeutic challenge in oropharyngeal squamous cell carcinoma (OPSCC). We aimed to devise novel objective imaging biomarkers for prediction of locoregional progression in HPV-associated OPSCC. Following manual lesion delineation, 1037 PET and 1037 CT radiomic features...

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Bibliographic Details
Main Authors: Stefan P. Haider, Kariem Sharaf, Tal Zeevi, Philipp Baumeister, Christoph Reichel, Reza Forghani, Benjamin H. Kann, Alexandra Petukhova, Benjamin L. Judson, Manju L. Prasad, Chi Liu, Barbara Burtness, Amit Mahajan, Seyedmehdi Payabvash
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Translational Oncology
Subjects:
Radiomics
Oropharyngeal squamous cell carcinoma
PET/CT
HPV
Imaging biomarker
Risk stratification
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523320303983

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http://www.sciencedirect.com/science/article/pii/S1936523320303983

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