mTOR controls endoplasmic reticulum–Golgi apparatus trafficking of VSVg in specific cell types

mTOR controls endoplasmic reticulum–Golgi apparatus trafficking of VSVg in specific cell types

Abstract Background Mammalian/mechanistic target of rapamycin (mTOR) complexes are essential for cell proliferation, growth, differentiation, and survival. mTORC1 hyperactivation occurs in the tuberous sclerosis complex (TSC). mTORC1 localizes to the surface of lysosomes, where Rheb activates it. Ho...

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Bibliographic Details
Main Authors: Alicja Koscielny, Ewa Liszewska, Katarzyna Machnicka, Michalina Wezyk, Katarzyna Kotulska, Jacek Jaworski
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Cellular & Molecular Biology Letters
Subjects:
MTOR
Endoplasmic reticulum
Golgi apparatus
VSVg
Tuberous sclerosis complex
Retention using selective hooks
Online Access:https://doi.org/10.1186/s11658-021-00262-z

Internet

https://doi.org/10.1186/s11658-021-00262-z

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