Structure of a DNA G-Quadruplex Related to Osteoporosis with a G-A Bulge Forming a <i>Pseudo-loop</i>

Bone remodeling is a fine-tuned process principally regulated by a cascade triggered by interaction of receptor activator of NF-kB (RANK) and RANK ligand (RANKL). Excessive activity of the <i>RANKL</i> gene leads to increased bone resorption and can influence the incidence of osteoporosi...

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Bibliographic Details
Main Authors: Martina Lenarčič Živković, Jan Rozman, Janez Plavec
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/25/20/4867