Age-related changes in human peripheral blood IGH repertoire following vaccination

Immune protection against pulmonary infections, such as seasonal flu and invasive pneumonia, is severely attenuated with age, and vaccination regimes for the elderly people often fail to elicit effective immune responses. We have previously shown that influenza and pneumococcal vaccine responses in...

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Bibliographic Details
Main Authors: Yu-Chang Bryan Wu, David eKipling, Deborah K Dunn-Walters
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-07-01
Series:Frontiers in Immunology
Subjects:
IgA
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00193/full