Serotonin system implication in L-DOPA-induced dyskinesia: from animal models to clinical investigations

In the recent years the serotonin system has emerged as a key player in the induction of L-DOPA-induced dyskinesia in animal models of Parkinson’s disease. In fact, serotonin neurons possess the enzymatic machinery able to convert exogenous L-DOPA to dopamine, and mediate its vesicular storage and r...

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Bibliographic Details
Main Authors: Manolo eCarta, Elisabetta eTronci
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-05-01
Series:Frontiers in Neurology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fneur.2014.00078/full