A novel 4-gene signature for overall survival prediction in lung adenocarcinoma patients with lymph node metastasis

A novel 4-gene signature for overall survival prediction in lung adenocarcinoma patients with lymph node metastasis

Abstract Background Lung adenocarcinoma (LUAD) patients experiencing lymph node metastasis (LNM) always exhibit poor clinical outcomes. A biomarker or gene signature that could predict survival in these patients would have a substantial clinical impact, allowing for earlier detection of mortality ri...

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Bibliographic Details
Main Authors: Yanfang Wang, Quanli Zhang, Zhaojia Gao, Shan Xin, Yanbo Zhao, Kai Zhang, Run Shi, Xuanwen Bao
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Cancer Cell International
Subjects:
Transcriptome
Lung adenocarcinoma (LUAD)
Lymph node metastasis (LNM)
mRNA signature
Weighted gene co-expression network analysis (WGCNA)
Overall survival (OS)
Online Access:http://link.springer.com/article/10.1186/s12935-019-0822-1

Internet

http://link.springer.com/article/10.1186/s12935-019-0822-1

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