The Tat Protein of HIV-1 Prevents the Loss of HSV-Specific Memory Adaptive Responses and Favors the Control of Viral Reactivation

The Tat Protein of HIV-1 Prevents the Loss of HSV-Specific Memory Adaptive Responses and Favors the Control of Viral Reactivation

The development of therapeutic strategies to control the reactivation of the Herpes Simplex Virus (HSV) is an unaddressed priority. In this study, we evaluated whether Tat, a HIV-1 protein displaying adjuvant functions, could improve previously established HSV-specific memory responses and prevent v...

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Bibliographic Details
Main Authors: Francesco Nicoli, Eleonora Gallerani, Mariaconcetta Sicurella, Salvatore Pacifico, Aurelio Cafaro, Barbara Ensoli, Peggy Marconi, Antonella Caputo, Riccardo Gavioli
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Vaccines
Subjects:
biologically active HIV-1 Tat protein
HSV-1 infection
HSV-1 immune responses
persistence of HSV-immune memory
Online Access:https://www.mdpi.com/2076-393X/8/2/274

Internet

https://www.mdpi.com/2076-393X/8/2/274

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