Circulating exosomal microRNAs as potential biomarkers of hepatic injury and inflammation in a murine model of glycogen storage disease type 1a

Circulating exosomal microRNAs as potential biomarkers of hepatic injury and inflammation in a murine model of glycogen storage disease type 1a

Most patients affected by glycogen storage disease type 1a (GSD1a), an inherited metabolic disorder caused by mutations in the enzyme glucose-6-phosphatase-α (G6Pase-α), develop renal and liver complications, including the development of hepatocellular adenoma/carcinoma. The purpose of this study wa...

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Bibliographic Details
Main Authors: Roberta Resaz, Davide Cangelosi, Martina Morini, Daniela Segalerba, Luca Mastracci, Federica Grillo, Maria Carla Bosco, Cristina Bottino, Irma Colombo, Alessandra Eva
Format: Article
Language:English
Published: The Company of Biologists 2020-09-01
Series:Disease Models & Mechanisms
Subjects:
glycogen storage disease type 1a
hepatocellular adenoma
biomarkers
exosomes
liver
microrna
Online Access:http://dmm.biologists.org/content/13/9/dmm043364

Internet

http://dmm.biologists.org/content/13/9/dmm043364

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