GSK3β Inhibition Promotes Efficient Myeloid and Lymphoid Hematopoiesis from Non-human Primate-Induced Pluripotent Stem Cells

GSK3β Inhibition Promotes Efficient Myeloid and Lymphoid Hematopoiesis from Non-human Primate-Induced Pluripotent Stem Cells

Advances in the scalable production of blood cells from induced pluripotent stem cells (iPSCs) open prospects for the clinical translation of de novo generated blood products, and evoke the need for preclinical evaluation of their efficacy, safety, and immunogenicity in large animal models. Due to s...

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Bibliographic Details
Main Authors: Saritha S. D'Souza, John Maufort, Akhilesh Kumar, Jiuchun Zhang, Kimberley Smuga-Otto, James A. Thomson, Igor I. Slukvin
Format: Article
Language:English
Published: Elsevier 2016-02-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671115003756

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http://www.sciencedirect.com/science/article/pii/S2213671115003756

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