GSK3β Inhibition Promotes Efficient Myeloid and Lymphoid Hematopoiesis from Non-human Primate-Induced Pluripotent Stem Cells
Advances in the scalable production of blood cells from induced pluripotent stem cells (iPSCs) open prospects for the clinical translation of de novo generated blood products, and evoke the need for preclinical evaluation of their efficacy, safety, and immunogenicity in large animal models. Due to s...
Main Authors: | Saritha S. D'Souza, John Maufort, Akhilesh Kumar, Jiuchun Zhang, Kimberley Smuga-Otto, James A. Thomson, Igor I. Slukvin |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2016-02-01
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Series: | Stem Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2213671115003756 |
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