Tuberculous granuloma formation is enhanced by a mycobacterium virulence determinant.
Granulomas are organized host immune structures composed of tightly interposed macrophages and other cells that form in response to a variety of persistent stimuli, both infectious and noninfectious. The tuberculous granuloma is essential for host containment of mycobacterial infection, although it...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2004-11-01
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| Series: | PLoS Biology |
| Online Access: | http://europepmc.org/articles/PMC524251?pdf=render |